Cargando…
Thymidine phosphorylase facilitates retinoic acid inducible gene-I induced endothelial dysfunction
Activation of nucleic acid sensors in endothelial cells (ECs) has been shown to drive inflammation across pathologies including cancer, atherosclerosis and obesity. We previously showed that enhancing cytosolic DNA sensing by inhibiting three prime exonuclease 1 (TREX1) in ECs led to EC dysfunction...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131517/ https://www.ncbi.nlm.nih.gov/pubmed/37100811 http://dx.doi.org/10.1038/s41419-023-05821-0 |