Evidence for Phosphorylation-Dependent, Dynamic, Regulation of mGlu5 and Homer2 in Expression of Cocaine Aversion in Mice

Cocaine-induced changes in the expression of the glutamate-related scaffolding protein Homer2 influence this drug’s psychostimulant and rewarding properties. In response to neuronal activity, Homer2 is phosphorylated on S117/S216 by calcium-calmodulin kinase IIα (CaMKIIα), which induces a rapid diss...

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Detalles Bibliográficos
Autores principales: Szumlinski, Karen K., Beltran, Jacqueline, van Doren, Eliyana, Jimenez Chavez, C. Leonardo, Domingo-Gonzalez, Racquel D., Reyes, Cindy M., Ary, Alexis W., Lang, Andrew, Guo, Weiruo, Worley, Paul F., Huber, Kimberly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2023
Materias:
Research Article: New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131536/
https://www.ncbi.nlm.nih.gov/pubmed/36973011
http://dx.doi.org/10.1523/ENEURO.0423-22.2023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131536/
https://www.ncbi.nlm.nih.gov/pubmed/36973011
http://dx.doi.org/10.1523/ENEURO.0423-22.2023

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