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CDKAL1 Drives the Maintenance of Cancer Stem‐Like Cells by Assembling the eIF4F Translation Initiation Complex

Cancer stem‐like cells (CSCs) have a unique translation mode, but little is understood about the process of elongation, especially the contribution of tRNA modifications to the maintenance of CSCs properties. Here, it is reported that, contrary to the initial aim, a tRNA‐modifying methylthiotransfer...

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Detalles Bibliográficos
Autores principales: Huang, Rongsheng, Yamamoto, Takahiro, Nakata, Eiji, Ozaki, Toshifumi, Kurozumi, Kazuhiko, Wei, Fanyan, Tomizawa, Kazuhito, Fujimura, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131790/
https://www.ncbi.nlm.nih.gov/pubmed/36786012
http://dx.doi.org/10.1002/advs.202206542