Human RSPO1 Mutation Represses Beige Adipocyte Thermogenesis and Contributes to Diet‐Induced Adiposity

Recent genetic evidence has linked WNT downstream mutations to fat distribution. However, the roles of WNTs in human obesity remain unclear. Here, the authors screen all Wnt‐related paracrine factors in 1994 obese cases and 2161 controls using whole‐exome sequencing (WES) and identify that 12 obese...

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Detalles Bibliográficos
Autores principales: Sun, Yingkai, Zhang, Juan, Hong, Jie, Zhang, Zhongyun, Lu, Peng, Gao, Aibo, Ni, Mengshan, Zhang, Zhiyin, Yang, Huanjie, Shen, Juan, Lu, Jieli, Xue, Wenzhi, Lv, Qianqian, Bi, Yufang, Zeng, Yi Arial, Gu, Weiqiong, Ning, Guang, Wang, Weiqing, Liu, Ruixin, Wang, Jiqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131814/
https://www.ncbi.nlm.nih.gov/pubmed/36755192
http://dx.doi.org/10.1002/advs.202207152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131814/
https://www.ncbi.nlm.nih.gov/pubmed/36755192
http://dx.doi.org/10.1002/advs.202207152

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