Copper-catalyzed asymmetric allylic alkylation of racemic inert cyclic allylic ethers under batch and flow conditions

Highly enantioselective Cu-catalyzed asymmetric allylic alkylation of racemic inert cyclic allylic ethers is accomplished in this work. The use of Grignard reagents in combination with BF(3)·OEt(2) and CuBr·SMe(2)/L2 is the key to enable employment of long-challenging low reactive allylic substrates...

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Detalles Bibliográficos
Autores principales: Li, Jun, Song, Xiao, Wang, Yan, Huang, Junrong, You, Hengzhi, Chen, Fen-Er
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132103/
https://www.ncbi.nlm.nih.gov/pubmed/37123175
http://dx.doi.org/10.1039/d3sc00127j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132103/
https://www.ncbi.nlm.nih.gov/pubmed/37123175
http://dx.doi.org/10.1039/d3sc00127j

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