Cargando…
Copper-catalyzed asymmetric allylic alkylation of racemic inert cyclic allylic ethers under batch and flow conditions
Highly enantioselective Cu-catalyzed asymmetric allylic alkylation of racemic inert cyclic allylic ethers is accomplished in this work. The use of Grignard reagents in combination with BF(3)·OEt(2) and CuBr·SMe(2)/L2 is the key to enable employment of long-challenging low reactive allylic substrates...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132103/ https://www.ncbi.nlm.nih.gov/pubmed/37123175 http://dx.doi.org/10.1039/d3sc00127j |