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IL-15 enhances HIV-1 infection by promoting survival and proliferation of CCR5(+)CD4(+) T cells
HIV-1 usually utilizes CCR5 as its coreceptor and rarely switches to a CXCR4-tropic virus until the late stage of infection. CCR5(+)CD4(+) T cells are the major virus-producing cells in viremic individuals as well as SIV-infected nonhuman primates. The differentiation of CCR5(+)CD4(+) T cells is ass...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Clinical Investigation
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132148/ https://www.ncbi.nlm.nih.gov/pubmed/36821374 http://dx.doi.org/10.1172/jci.insight.166292 |