CD11c(+) macrophages are proangiogenic and necessary for experimental choroidal neovascularization

Patients with neovascular AMD (nAMD) suffer vision loss from destructive angiogenesis, termed choroidal neovascularization (CNV). Macrophages are found in CNV lesions from patients with nAMD. Additionally, Ccr2(–/–) mice, which lack classical monocyte–derived macrophages, show reduced CNV size. Howe...

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Detalles Bibliográficos
Autores principales: Droho, Steven, Rajesh, Amrita, Cuda, Carla M., Perlman, Harris, Lavine, Jeremy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132149/
https://www.ncbi.nlm.nih.gov/pubmed/36821388
http://dx.doi.org/10.1172/jci.insight.168142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132149/
https://www.ncbi.nlm.nih.gov/pubmed/36821388
http://dx.doi.org/10.1172/jci.insight.168142

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