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CD11c(+) macrophages are proangiogenic and necessary for experimental choroidal neovascularization
Patients with neovascular AMD (nAMD) suffer vision loss from destructive angiogenesis, termed choroidal neovascularization (CNV). Macrophages are found in CNV lesions from patients with nAMD. Additionally, Ccr2(–/–) mice, which lack classical monocyte–derived macrophages, show reduced CNV size. Howe...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Clinical Investigation
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132149/ https://www.ncbi.nlm.nih.gov/pubmed/36821388 http://dx.doi.org/10.1172/jci.insight.168142 |