Lenvatinib or anti-VEGF in combination with anti–PD-1 differentially augments antitumor activity in melanoma

Targeting tumor-associated blood vessels to increase immune infiltration may enhance treatment effectiveness, yet limited data exist regarding anti-angiogenesis effects on the tumor microenvironment (TME). We hypothesized that dual targeting of angiogenesis with immune checkpoints would improve both...

Descripción completa

Detalles Bibliográficos
Autores principales: Tran, Thuy T., Caulfield, Jasmine, Zhang, Lin, Schoenfeld, David, Djureinovic, Dijana, Chiang, Veronica L., Oria, Victor, Weiss, Sarah A., Olino, Kelly, Jilaveanu, Lucia B., Kluger, Harriet M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132152/
https://www.ncbi.nlm.nih.gov/pubmed/36821392
http://dx.doi.org/10.1172/jci.insight.157347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132152/
https://www.ncbi.nlm.nih.gov/pubmed/36821392
http://dx.doi.org/10.1172/jci.insight.157347

Ejemplares similares