A miRNA/CXCR4 signaling axis impairs monopoiesis and angiogenesis in diabetic critical limb ischemia

Patients with peripheral artery disease (PAD) and diabetes have the highest risk of critical limb ischemia (CLI) and amputation, yet the underlying mechanisms remain incompletely understood. MicroRNA (miRNA) sequencing of plasma from diabetic patients with or without CLI was compared to diabetic mic...

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Detalles Bibliográficos
Autores principales: Cheng, Henry S., Zhuang, Rulin, Pérez-Cremades, Daniel, Chen, Jingshu, Jamaiyar, Anurag, Wu, Winona, Sausen, Grasiele, Tzani, Aspasia, Plutzky, Jorge, Henao-Mejia, Jorge, Goodney, Philip P., Creager, Mark A., Sabatine, Marc S., Bonaca, Marc P., Feinberg, Mark W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132154/
https://www.ncbi.nlm.nih.gov/pubmed/36821386
http://dx.doi.org/10.1172/jci.insight.163360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132154/
https://www.ncbi.nlm.nih.gov/pubmed/36821386
http://dx.doi.org/10.1172/jci.insight.163360

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