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Mapping the metabolic reprogramming induced by sodium-glucose cotransporter 2 inhibition

Diabetes is associated with increased risk for kidney disease, heart failure, and mortality. Sodium-glucose cotransporter 2 inhibitors (SGLT2i) prevent these adverse outcomes; however, the mechanisms involved are not clear. We generated a roadmap of the metabolic alterations that occur in different...

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Detalles Bibliográficos
Autores principales: Kogot-Levin, Aviram, Riahi, Yael, Abramovich, Ifat, Mosenzon, Ofri, Agranovich, Bella, Kadosh, Liat, Ben-Haroush Schyr, Rachel, Kleiman, Doron, Hinden, Liad, Cerasi, Erol, Ben-Zvi, Danny, Bernal-Mizrachi, Ernesto, Tam, Joseph, Gottlieb, Eyal, Leibowitz, Gil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132155/
https://www.ncbi.nlm.nih.gov/pubmed/36809274
http://dx.doi.org/10.1172/jci.insight.164296