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Cannabinoid enhancement of lncRNA MMP25-AS1/MMP25 interaction reduces neutrophil infiltration and intestinal epithelial injury in HIV/SIV infection

Intestinal epithelial barrier dysfunction, a hallmark of HIV/SIV infection, persists despite viral suppression by combination antiretroviral therapy (cART). Emerging evidence suggests a critical role for long noncoding RNAs (lncRNAs) in maintaining epithelial homeostasis. We simultaneously profiled...

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Detalles Bibliográficos
Autores principales: Premadasa, Lakmini S., Lee, Eunhee, McDew-White, Marina, Alvarez, Xavier, Jayakumar, Sahana, Ling, Binhua, Okeoma, Chioma M., Byrareddy, Siddappa N., Kulkarni, Smita, Mohan, Mahesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132162/
https://www.ncbi.nlm.nih.gov/pubmed/37036007
http://dx.doi.org/10.1172/jci.insight.167903