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Immune profiling of SARS-CoV-2 infection during pregnancy reveals NK cell and γδ T cell perturbations

Pregnancy poses a greater risk for severe COVID-19; however, underlying immunological changes associated with SARS-CoV-2 during pregnancy are poorly understood. We defined immune responses to SARS-CoV-2 in unvaccinated pregnant and nonpregnant women with acute and convalescent COVID-19, quantifying...

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Detalles Bibliográficos
Autores principales: Habel, Jennifer R., Chua, Brendon Y., Kedzierski, Lukasz, Selva, Kevin J., Damelang, Timon, Haycroft, Ebene R., Nguyen, Thi H.O., Koay, Hui-Fern, Nicholson, Suellen, McQuilten, Hayley A., Jia, Xiaoxiao, Allen, Lilith F., Hensen, Luca, Zhang, Wuji, van de Sandt, Carolien E., Neil, Jessica A., Pragastis, Katherine, Lau, Jillian S.Y., Jumarang, Jaycee, Allen, E. Kaitlynn, Amanant, Fatima, Krammer, Florian, Wragg, Kathleen M., Juno, Jennifer A., Wheatley, Adam K., Tan, Hyon-Xhi, Pell, Gabrielle, Walker, Susan, Audsley, Jennifer, Reynaldi, Arnold, Thevarajan, Irani, Denholm, Justin T., Subbarao, Kanta, Davenport, Miles P., Hogarth, P. Mark, Godfrey, Dale I., Cheng, Allen C., Tong, Steven Y.C., Bond, Katherine, Williamson, Deborah A., McMahon, James H., Thomas, Paul G., Pannaraj, Pia S., James, Fiona, Holmes, Natasha E., Smibert, Olivia C., Trubiano, Jason A., Gordon, Claire L., Chung, Amy W., Whitehead, Clare L., Kent, Stephen J., Lappas, Martha, Rowntree, Louise C., Kedzierska, Katherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132165/
https://www.ncbi.nlm.nih.gov/pubmed/37036008
http://dx.doi.org/10.1172/jci.insight.167157