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A convergent fragment coupling strategy to access quaternary stereogenic centers

The formation of quaternary stereogenic centers via convergent fragment coupling is a longstanding challenge in organic synthesis. Here, we report a strategy for the formation of quaternary stereogenic centers in polycyclic systems based upon the semi-pinacol reaction. In the key transformation, two...

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Detalles Bibliográficos
Autores principales: Kerkovius, Jeff K., Wong, Alice R., Mak, Victor W., Reisman, Sarah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132171/
https://www.ncbi.nlm.nih.gov/pubmed/37123185
http://dx.doi.org/10.1039/d2sc07023e