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AURKB Enhances Chromosomal Remodeling of Telomeric Genes and Accelerates Tumorigenesis of Uveal Melanoma

PURPOSE: Uveal melanoma (UM) is the most common intraocular malignancy in adults developing liver metastases, threatening a patient's life. Current therapeutics failed to significantly improve the survival of patients with UM. Thus, the discovery of potent drugs is imminent. METHODS: Integrated...

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Detalles Bibliográficos
Autores principales: Wang, Huixue, Pan, Hui, Huang, Xiaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132317/
https://www.ncbi.nlm.nih.gov/pubmed/37079315
http://dx.doi.org/10.1167/iovs.64.4.23