Mice Deficient in TAZ (Wwtr1) Demonstrate Clinical Features of Late-Onset Fuchs’ Endothelial Corneal Dystrophy

PURPOSE: We sought to define the role of Wwtr1 in murine ocular structure and function and determine the role of mechanotransduction in Fuchs’ endothelial corneal dystrophy (FECD), with emphasis on interactions between corneal endothelial cells (CEnCs) and Descemet's membrane (DM). METHODS: A W...

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Detalles Bibliográficos
Autores principales: Leonard, Brian C., Park, Sangwan, Kim, Soohyun, Young, Laura J., Jalilian, Iman, Cosert, Krista, Zhang, Xunzhi, Skeie, Jessica M., Shevalye, Hanna, Echeverria, Nayeli, Rozo, Vanessa, Gong, Xin, Xing, Chao, Murphy, Christopher J., Greiner, Mark A., Mootha, V. Vinod, Raghunathan, Vijay Krishna, Thomasy, Sara M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Cornea
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132321/
https://www.ncbi.nlm.nih.gov/pubmed/37074694
http://dx.doi.org/10.1167/iovs.64.4.22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132321/
https://www.ncbi.nlm.nih.gov/pubmed/37074694
http://dx.doi.org/10.1167/iovs.64.4.22

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