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Tim-3 regulates the immunosuppressive function of decidual MDSCs via the Fyn-STAT3-C/EBPβ pathway during Toxoplasma gondii infection

Myeloid-derived suppressor cells (MDSCs) play a key role in maintaining maternal-fetal tolerance for a successful pregnancy, but the role of MDSCs in abnormal pregnancy caused by Toxoplasma gondii infection is unknown. Herein, we revealed a distinct mechanism by which T-cell immunoglobulin domain an...

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Detalles Bibliográficos
Autores principales: Qi, Houbao, Li, Yuantao, Liu, Xianbing, Jiang, Yuzhu, Li, Zhidan, Xu, Xiaoyan, Zhang, Haixia, Hu, Xuemei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132691/
https://www.ncbi.nlm.nih.gov/pubmed/37058540
http://dx.doi.org/10.1371/journal.ppat.1011329