Premature senescence of the liver in Alagille patients

INTRODUCTION: Alagille syndrome (ALGS) is an autosomal dominant disease characterized by a multisystem involvement including bile duct paucity and cholestasis, caused by JAG1 or NOTCH2 mutations in most of the cases. Jagged1-Notch2 interactions are known to be crucial for intrahepatic biliary tract...

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Detalles Bibliográficos
Autores principales: Jannone, Giulia, de Magnée, Catherine, Tambucci, Roberto, Evraerts, Jonathan, Ravau, Joachim, Najimi, Mustapha, Sokal, Etienne Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132695/
https://www.ncbi.nlm.nih.gov/pubmed/37099537
http://dx.doi.org/10.1371/journal.pone.0285019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132695/
https://www.ncbi.nlm.nih.gov/pubmed/37099537
http://dx.doi.org/10.1371/journal.pone.0285019

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