Coupling of protein condensates to ordered lipid domains determines functional membrane organization

During T cell activation, the transmembrane adaptor protein LAT (linker for activation of T cells) forms biomolecular condensates with Grb2 and Sos1, facilitating signaling. LAT has also been associated with cholesterol-rich condensed lipid domains; However, the potential coupling between protein co...

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Detalles Bibliográficos
Autores principales: Wang, Hong-Yin, Chan, Sze Ham, Dey, Simli, Castello-Serrano, Ivan, Rosen, Michael K., Ditlev, Jonathon A., Levental, Kandice R., Levental, Ilya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132753/
https://www.ncbi.nlm.nih.gov/pubmed/37126554
http://dx.doi.org/10.1126/sciadv.adf6205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132753/
https://www.ncbi.nlm.nih.gov/pubmed/37126554
http://dx.doi.org/10.1126/sciadv.adf6205

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