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An ERK-dependent molecular switch antagonizes fibrosis and promotes regeneration in spiny mice (Acomys)

Although most mammals heal injured tissues and organs with scarring, spiny mice (Acomys) naturally regenerate skin and complex musculoskeletal tissues. Now, the core signaling pathways driving mammalian tissue regeneration are poorly characterized. Here, we show that, while immediate extracellular s...

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Detalles Bibliográficos
Autores principales: Tomasso, Antonio, Koopmans, Tim, Lijnzaad, Philip, Bartscherer, Kerstin, Seifert, Ashley W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132760/
https://www.ncbi.nlm.nih.gov/pubmed/37126559
http://dx.doi.org/10.1126/sciadv.adf2331