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Evaluation of DNA methylation biomarkers ASCL1 and LHX8 on HPV-positive self-collected samples from primary HPV-based screening

BACKGROUND: Host-cell DNA methylation analysis can be used to triage women with high-risk human papillomavirus (HPV)-positive self-collected cervicovaginal samples, but current data are restricted to under-/never-screened women and referral populations. This study evaluated triage performance in wom...

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Detalles Bibliográficos
Autores principales: Verhoef, Lisanne, Bleeker, Maaike C. G., Polman, Nicole, Steenbergen, Renske D. M., Ebisch, Renée M. F., Melchers, Willem J. G., Bekkers, Ruud L. M., Molijn, Anco C., Quint, Wim G., van Kemenade, Folkert, Meijer, Chris J. L. M., Berkhof, Johannes, Heideman, Daniëlle A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132796/
https://www.ncbi.nlm.nih.gov/pubmed/37100874
http://dx.doi.org/10.1038/s41416-023-02277-z