Mesaconine alleviates doxorubicin-triggered cardiotoxicity and heart failure by activating PINK1-dependent cardiac mitophagy

Aberrant mitophagy has been identified as a driver for energy metabolism disorder in most cardiac pathological processes. However, finding effective targeted agents and uncovering their precise modulatory mechanisms remain unconquered. Fuzi, the lateral roots of Aconitum carmichaelii, shows unique e...

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Detalles Bibliográficos
Autores principales: Zhou, Ji-Chao, Jin, Cai-Cai, Wei, Xiao-Li, Xu, Rui-Bing, Wang, Ruo-Yu, Zhang, Zhi-Meng, Tang, Bo, Yu, Jin-Mei, Yu, Jiao-Jiao, Shang, Shuang, Lv, Xiao-Xi, Hua, Fang, Li, Ping-Ping, Hu, Zhuo-Wei, Shen, Yong-Mei, Wang, Feng-Peng, Ma, Xiu-Ying, Cui, Bing, Geng, Fu-Neng, Zhang, Xiao-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132857/
https://www.ncbi.nlm.nih.gov/pubmed/37124193
http://dx.doi.org/10.3389/fphar.2023.1118017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132857/
https://www.ncbi.nlm.nih.gov/pubmed/37124193
http://dx.doi.org/10.3389/fphar.2023.1118017

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