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Evaluation of Cellular Immune Response to Adeno-Associated Virus-Based Gene Therapy
The number of approved or investigational late phase viral vector gene therapies (GTx) has been rapidly growing. The adeno-associated virus vector (AAV) technology continues to be the most used GTx platform of choice. The presence of pre-existing anti-AAV immunity has been firmly established and is...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132926/ https://www.ncbi.nlm.nih.gov/pubmed/37101079 http://dx.doi.org/10.1208/s12248-023-00814-5 |