Inferring early genetic progression in cancers with unobtainable premalignant disease

Analysis of premalignant tissue has identified the typical order of somatic events leading to invasive tumors in several cancer types. For other cancers, premalignant tissue is unobtainable, leaving genetic progression unknown. Here, we demonstrate how to infer progression from exome sequencing of p...

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Detalles Bibliográficos
Autores principales: Leshchiner, Ignaty, Mroz, Edmund A., Cha, Justin, Rosebrock, Daniel, Spiro, Oliver, Bonilla-Velez, Juliana, Faquin, William C., Lefranc-Torres, Armida, Lin, Derrick T., Michaud, William A., Getz, Gad, Rocco, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132986/
https://www.ncbi.nlm.nih.gov/pubmed/37081260
http://dx.doi.org/10.1038/s43018-023-00533-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132986/
https://www.ncbi.nlm.nih.gov/pubmed/37081260
http://dx.doi.org/10.1038/s43018-023-00533-y

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