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Dedifferentiation maintains melanocyte stem cells in a dynamic niche

For unknow reasons, the melanocyte stem cell (McSC) system fails earlier than other adult stem cell populations(1), which leads to hair greying in most humans and mice(2,3). Current dogma states that McSCs are reserved in an undifferentiated state in the hair follicle niche, physically segregated fr...

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Detalles Bibliográficos
Autores principales: Sun, Qi, Lee, Wendy, Hu, Hai, Ogawa, Tatsuya, De Leon, Sophie, Katehis, Ioanna, Lim, Chae Ho, Takeo, Makoto, Cammer, Michael, Taketo, M. Mark, Gay, Denise L., Millar, Sarah E., Ito, Mayumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132989/
https://www.ncbi.nlm.nih.gov/pubmed/37076619
http://dx.doi.org/10.1038/s41586-023-05960-6