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Comparative analysis of EpCAM high-expressing and low-expressing circulating tumour cells with regard to their clonal relationship and clinical value

BACKGROUND: Circulating tumour cells (CTCs) are mainly enriched based on the epithelial cell adhesion molecule (EpCAM). Although it was shown that an EpCAM low-expressing CTC fraction is not captured by such approaches, knowledge about its prognostic and predictive relevance and its relation to EpCA...

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Detalles Bibliográficos
Autores principales: Franken, André, Kraemer, Annika, Sicking, Alicia, Watolla, Meike, Rivandi, Mahdi, Yang, Liwen, Warfsmann, Jens, Polzer, Bernhard M., Friedl, Thomas W. P., Meier-Stiegen, Franziska, Stoecklein, Nikolas H., Dayan, Davut, Riethdorf, Sabine, Mueller, Volkmar, Pantel, Klaus, Koch, André, Hartkopf, Andreas D., Krawczyk, Natalia, Ruckhaeberle, Eugen, Niederacher, Dieter, Fehm, Tanja, Neubauer, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133238/
https://www.ncbi.nlm.nih.gov/pubmed/36823365
http://dx.doi.org/10.1038/s41416-023-02179-0