Smart thrombosis inhibitors without bleeding side effects via charge tunable ligand design

Current treatments to prevent thrombosis, namely anticoagulants and platelets antagonists, remain complicated by the persistent risk of bleeding. Improved therapeutic strategies that diminish this risk would have a huge clinical impact. Antithrombotic agents that neutralize and inhibit polyphosphate...

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Detalles Bibliográficos
Autores principales: La, Chanel C., Smith, Stephanie A., Vappala, Sreeparna, Adili, Reheman, Luke, Catherine E., Abbina, Srinivas, Luo, Haiming D., Chafeeva, Irina, Drayton, Matthew, Creagh, Louise A., de Guadalupe Jaraquemada-Peláez, Maria, Rhoads, Nicole, Kalathottukaren, Manu Thomas, Henke, Peter K., Straus, Suzana K., Du, Caigan, Conway, Edward M., Holinstat, Michael, Haynes, Charles A., Morrissey, James H., Kizhakkedathu, Jayachandran N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133246/
https://www.ncbi.nlm.nih.gov/pubmed/37100783
http://dx.doi.org/10.1038/s41467-023-37709-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133246/
https://www.ncbi.nlm.nih.gov/pubmed/37100783
http://dx.doi.org/10.1038/s41467-023-37709-0

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