A CRISPR/Cas9-generated mutation in the zebrafish orthologue of PPP2R3B causes idiopathic scoliosis

Idiopathic scoliosis (IS) is the deformation and/or abnormal curvature of the spine that develops progressively after birth. It is a very common condition, affecting approximately 4% of the general population, yet the genetic and mechanistic causes of IS are poorly understood. Here, we focus on PPP2...

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Detalles Bibliográficos
Autores principales: Seda, Marian, Crespo, Berta, Corcelli, Michelangelo, Osborn, Daniel P., Jenkins, Dagan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133272/
https://www.ncbi.nlm.nih.gov/pubmed/37100808
http://dx.doi.org/10.1038/s41598-023-33589-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133272/
https://www.ncbi.nlm.nih.gov/pubmed/37100808
http://dx.doi.org/10.1038/s41598-023-33589-y

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