Metabolomics analysis reveals cytotoxic effects of ouabain towards psoriatic keratinocytes via impairment of glutathione metabolism

Ouabain is a cardiac glycoside long studied for treating heart diseases, but the attempts to evaluate its anti-psoriatic activity have not been reported. We aimed to explore the effects of ouabain on proliferation and metabolism towards psoriatic keratinocytes. In human HaCaT keratinocytes, ouabain...

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Detalles Bibliográficos
Autores principales: Zhou, Xuan, Fei, Fei, Song, Wei, Ma, Hehua, Xu, Zhenzhen, Yue, Jing, Cao, Bei, Sun, Runbin, Zhao, Yu, Yang, Yuanxun, Jiang, Junyi, Geng, Yan, Weng, Zuyi, Li, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133367/
https://www.ncbi.nlm.nih.gov/pubmed/36856826
http://dx.doi.org/10.1007/s00438-023-02001-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133367/
https://www.ncbi.nlm.nih.gov/pubmed/36856826
http://dx.doi.org/10.1007/s00438-023-02001-9

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