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Sequence-structure-function relationships in the microbial protein universe

For the past half-century, structural biologists relied on the notion that similar protein sequences give rise to similar structures and functions. While this assumption has driven research to explore certain parts of the protein universe, it disregards spaces that don’t rely on this assumption. Her...

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Detalles Bibliográficos
Autores principales: Koehler Leman, Julia, Szczerbiak, Pawel, Renfrew, P. Douglas, Gligorijevic, Vladimir, Berenberg, Daniel, Vatanen, Tommi, Taylor, Bryn C., Chandler, Chris, Janssen, Stefan, Pataki, Andras, Carriero, Nick, Fisk, Ian, Xavier, Ramnik J., Knight, Rob, Bonneau, Richard, Kosciolek, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133388/
https://www.ncbi.nlm.nih.gov/pubmed/37100781
http://dx.doi.org/10.1038/s41467-023-37896-w