Latent disease similarities and therapeutic repurposing possibilities uncovered by multi-modal generative topic modeling of human diseases

MOTIVATION: Human diseases are characterized by multiple features such as their pathophysiological, molecular and genetic changes. The rapid expansion of such multi-modal disease-omics space provides an opportunity to re-classify diverse human diseases and to uncover their latent molecular similarit...

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Detalles Bibliográficos
Autores principales: Kozawa, Satoshi, Yokoyama, Hirona, Urayama, Kyoji, Tejima, Kengo, Doi, Hotaka, Takagi, Shunki, Sato, Thomas N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133403/
https://www.ncbi.nlm.nih.gov/pubmed/37123453
http://dx.doi.org/10.1093/bioadv/vbad047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133403/
https://www.ncbi.nlm.nih.gov/pubmed/37123453
http://dx.doi.org/10.1093/bioadv/vbad047

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