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Dynamics of a model for the degradation mechanism of aggregated α-synuclein in Parkinson's disease
Accumulation of the misfolded synaptic protein α-synuclein (αSyn(*)) is a hallmark of neurodegenerative disease in Parkinson's disease (PD). Recent studies suggest that the autophagy lysosome pathway (ALP) including both the Beclin1-associated and mTOR-signaling pathways is involved in the αSyn...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133481/ https://www.ncbi.nlm.nih.gov/pubmed/37122994 http://dx.doi.org/10.3389/fncom.2023.1068150 |