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The effects of mild hypothermia on the electrode insertion trauma in a murine whole organ cochlea culture

INTRODUCTION: Local therapeutic hypothermia (32°C) has been linked experimentally to an otoprotective effect in the electrode insertion trauma. The pathomechanism of the electrode insertion trauma is connected to the activation of apoptosis and necrosis pathways, pro-inflammatory and fibrotic mechan...

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Detalles Bibliográficos
Autores principales: Schmutzhard, Joachim, Bader, Werner, Gottfried, Timo, Dejaco, Daniel, Glückert, Rudolf, Dudas, Joszef, Schrott-Fischer, Annelies
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133490/
https://www.ncbi.nlm.nih.gov/pubmed/37123355
http://dx.doi.org/10.3389/fnins.2023.1112243