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The proteasome: A key modulator of nervous system function, brain aging, and neurodegenerative disease
The proteasome is a large multi-subunit protease responsible for the degradation and removal of oxidized, misfolded, and polyubiquitinated proteins. The proteasome plays critical roles in nervous system processes. This includes maintenance of cellular homeostasis in neurons. It also includes roles i...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133520/ https://www.ncbi.nlm.nih.gov/pubmed/37123415 http://dx.doi.org/10.3389/fcell.2023.1124907 |