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The proteasome: A key modulator of nervous system function, brain aging, and neurodegenerative disease

The proteasome is a large multi-subunit protease responsible for the degradation and removal of oxidized, misfolded, and polyubiquitinated proteins. The proteasome plays critical roles in nervous system processes. This includes maintenance of cellular homeostasis in neurons. It also includes roles i...

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Detalles Bibliográficos
Autores principales: Davidson, Kanisa, Pickering, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133520/
https://www.ncbi.nlm.nih.gov/pubmed/37123415
http://dx.doi.org/10.3389/fcell.2023.1124907