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Multivariate genome-wide association analysis by iterative hard thresholding

MOTIVATION: In a genome-wide association study, analyzing multiple correlated traits simultaneously is potentially superior to analyzing the traits one by one. Standard methods for multivariate genome-wide association study operate marker-by-marker and are computationally intensive. RESULTS: We pres...

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Detalles Bibliográficos
Autores principales: Chu, Benjamin B, Ko, Seyoon, Zhou, Jin J, Jensen, Aubrey, Zhou, Hua, Sinsheimer, Janet S, Lange, Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133532/
https://www.ncbi.nlm.nih.gov/pubmed/37067496
http://dx.doi.org/10.1093/bioinformatics/btad193