Ontogeny of CYP3A and UGT activity in preterm piglets: a translational model for drug metabolism in preterm newborns

Despite considerable progress in understanding drug metabolism in the human pediatric population, data remains scarce in preterm neonates. Improving our knowledge of the ADME properties in this vulnerable age group is of utmost importance to avoid suboptimal dosing, which may lead to adverse drug re...

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Detalles Bibliográficos
Autores principales: Buyssens, Laura, Valenzuela, Allan, Prims, Sara, Ayuso, Miriam, Thymann, Thomas, Van Ginneken, Chris, Van Cruchten, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133700/
https://www.ncbi.nlm.nih.gov/pubmed/37124224
http://dx.doi.org/10.3389/fphar.2023.1177541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133700/
https://www.ncbi.nlm.nih.gov/pubmed/37124224
http://dx.doi.org/10.3389/fphar.2023.1177541

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