Pathological bile acid concentrations in chronic cholestasis cause adipose mitochondrial defects

BACKGROUND & AIMS: Although fat loss is observed in patients with cholestasis, how chronically elevated bile acids (BAs) impact white and brown fat depots remains obscure. METHODS: To determine the direct effect of pathological levels of BAs on lipid accumulation and mitochondrial function, prim...

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Detalles Bibliográficos
Autores principales: Zhou, Weinan, VanDuyne, Philip, Zhang, Chi, Liu, Yushan, Riessen, Ryan, Barragan, Maribel, Rowitz, Blair M., Teran-Garcia, Margarita, Boppart, Stephen A., Anakk, Sayeepriyadarshini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133756/
https://www.ncbi.nlm.nih.gov/pubmed/37122689
http://dx.doi.org/10.1016/j.jhepr.2023.100714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133756/
https://www.ncbi.nlm.nih.gov/pubmed/37122689
http://dx.doi.org/10.1016/j.jhepr.2023.100714

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