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Structural insights into ubiquitin chain cleavage by Legionella ovarian tumor deubiquitinases

Although ubiquitin is found only in eukaryotes, several pathogenic bacteria and viruses possess proteins that hinder the host ubiquitin system. Legionella, a gram-negative intracellular bacterium, possesses an ovarian tumor (OTU) family of deubiquitinases (Lot DUBs). Herein, we describe the molecula...

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Detalles Bibliográficos
Autores principales: Kang, Sangwoo, Kim, Gyuhee, Choi, Minhyeong, Jeong, Minwoo, van der Heden van Noort, Gerbrand J, Roh, Soung-Hun, Shin, Donghyuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133868/
https://www.ncbi.nlm.nih.gov/pubmed/37100438
http://dx.doi.org/10.26508/lsa.202201876