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Increased methylglyoxal formation in plasma and tissues during a glucose tolerance test is derived from exogenous glucose

The dicarbonyl compound methylglyoxal (MGO) is a major precursor in the formation of advanced glycation endproducts (AGEs). MGO and AGEs are increased in subjects with diabetes and are associated with fatal and nonfatal cardiovascular disease. Previously, we have shown that plasma MGO concentrations...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaodi, Scheijen, Jean L.J.M., Stehouwer, Coen D.A., Wouters, Kristiaan, Schalkwijk, Casper G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133870/
https://www.ncbi.nlm.nih.gov/pubmed/36661051
http://dx.doi.org/10.1042/CS20220753