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Next-generation poly-L-histidine formulations for miRNA mimic delivery

Many diseases, especially cancer, are caused by the abnormal expression of non-coding microRNAs (miRNAs), which regulate gene expression, leading to the development of miRNA-based therapeutics. Synthetic miRNA inhibitors have shown promising efficacy in blocking the activity of aberrant miRNAs that...

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Detalles Bibliográficos
Autores principales: Kasina, Vishal, Wahane, Aniket, Liu, Chung-Hao, Yang, Lin, Nieh, Mu-Ping, Slack, Frank J., Bahal, Raman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133875/
https://www.ncbi.nlm.nih.gov/pubmed/37123088
http://dx.doi.org/10.1016/j.omtm.2023.03.015