Successful treatment of refractory chylothorax with MEK inhibitor trametinib in a child with Noonan syndrome: case report

BACKGROUND: Refractory chylous effusions due to lymphatic dysplasia related to Noonan syndrome cause significant morbidity and mortality due to protein and immunoglobulin losses. Very few cases have been published reporting successful treatment of patients with trametinib where all conventional trea...

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Detalles Bibliográficos
Autores principales: Hribernik, Ines, Brooks, Teresa, Dunlop-Jones, Alix, Bentham, James R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133994/
https://www.ncbi.nlm.nih.gov/pubmed/37123650
http://dx.doi.org/10.1093/ehjcr/ytad190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133994/
https://www.ncbi.nlm.nih.gov/pubmed/37123650
http://dx.doi.org/10.1093/ehjcr/ytad190

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