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Assessment of anti-HIV-1 guide RNA efficacy in cells containing the viral target sequence, corresponding gRNA, and CRISPR/Cas9
The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 gene editing system has been shown to be effective at inhibiting human immunodeficiency virus type 1 (HIV-1). Studies have not consistently used a trackable dual reporter system to determine what cells received the Cas9/gRNA...
Autores principales: | Allen, Alexander G., Chung, Cheng-Han, Worrell, Stephen D., Nwaozo, Glad, Madrid, Rebekah, Mele, Anthony R., Dampier, Will, Nonnemacher, Michael R., Wigdahl, Brian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134072/ https://www.ncbi.nlm.nih.gov/pubmed/37124096 http://dx.doi.org/10.3389/fgeed.2023.1101483 |
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