Cargando…

Poor association between dihydropyrimidine dehydrogenase ( DPYD ) genotype and fluoropyrimidine‐induced toxicity in an Asian population

OBJECTIVE: Dihydropyrimidine dehydrogenase (DPYD) genotype is closely associated with fluoropyrimidine (FP)‐induced toxicities in Caucasian population and European Medicines Agency now recommends DPYD genotype‐based FP dosing strategy. PATIENTS AND METHODS: The current study aimed to investigate the...

Descripción completa

Detalles Bibliográficos
Autores principales: Kanai, Masashi, Kawaguchi, Takahisa, Kotaka, Masahito, Manaka, Dai, Hasegawa, Junichi, Takagane, Akinori, Munemoto, Yoshinori, Kato, Takeshi, Eto, Tetsuya, Touyama, Tetsuo, Matsui, Takanori, Shinozaki, Katsunori, Matsumoto, Shigemi, Mizushima, Tsunekazu, Mori, Masaki, Sakamoto, Junichi, Ohtsu, Atsushi, Yoshino, Takayuki, Saji, Shigetoyo, Matsuda, Fumihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134304/
https://www.ncbi.nlm.nih.gov/pubmed/36524458
http://dx.doi.org/10.1002/cam4.5541