Apoptin causes apoptosis in HepG‐2 cells via Ca(2+) imbalance and activation of the mitochondrial apoptotic pathway

BACKGROUND: Apoptin is derived from the chicken anemia virus and exhibits specific cytotoxic effects against tumor cells. Herein, we found that Apoptin induced a strong and lasting endoplasmic reticulum (ER) stress response, Ca(2+) imbalance, and triggered the mitochondrial apoptotic pathway. The ai...

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Detalles Bibliográficos
Autores principales: Yu, Xiaoyang, Wang, Tongxing, Li, Yue, Li, Yiquan, Bai, Bing, Fang, Jinbo, Han, Jicheng, Li, Shanzhi, Xiu, Zhiru, Liu, Zirui, Yang, Xia, Li, Yaru, Zhu, Guangze, Jin, Ningyi, Shang, Chao, Li, Xiao, Zhu, Yilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
RESEARCH ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134343/
https://www.ncbi.nlm.nih.gov/pubmed/36515089
http://dx.doi.org/10.1002/cam4.5528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134343/
https://www.ncbi.nlm.nih.gov/pubmed/36515089
http://dx.doi.org/10.1002/cam4.5528

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