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SLC12A5 promotes hepatocellular carcinoma growth and ferroptosis resistance by inducing ER stress and cystine transport changes

BACKGROUND: Hepatocellular carcinoma (HCC) has a poor prognosis and new effective treatments are needed. SLC12A5 plays important roles in multiple complex pathological states and is overexpressed in a variety of malignancies. However, the effects of SLC12A5 in HCC have not been determined. METHODS:...

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Detalles Bibliográficos
Autores principales: Tong, Qing, Qin, Wei, Li, Zheng‐Hao, Liu, Chun, Wang, Zi‐Cheng, Chu, Yuan, Xu, Xun‐Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134347/
https://www.ncbi.nlm.nih.gov/pubmed/36645171
http://dx.doi.org/10.1002/cam4.5605