Cargando…
SLC12A5 promotes hepatocellular carcinoma growth and ferroptosis resistance by inducing ER stress and cystine transport changes
BACKGROUND: Hepatocellular carcinoma (HCC) has a poor prognosis and new effective treatments are needed. SLC12A5 plays important roles in multiple complex pathological states and is overexpressed in a variety of malignancies. However, the effects of SLC12A5 in HCC have not been determined. METHODS:...
Autores principales: | Tong, Qing, Qin, Wei, Li, Zheng‐Hao, Liu, Chun, Wang, Zi‐Cheng, Chu, Yuan, Xu, Xun‐Di |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134347/ https://www.ncbi.nlm.nih.gov/pubmed/36645171 http://dx.doi.org/10.1002/cam4.5605 |
Ejemplares similares
-
Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy
por: Koppula, Pranavi, et al.
Publicado: (2020) -
CISD3 inhibition drives cystine-deprivation induced ferroptosis
por: Li, Yanchun, et al.
Publicado: (2021) -
Multifaceted mechanisms mediating cystine starvation-induced ferroptosis
por: Shi, Zhennan, et al.
Publicado: (2021) -
Stress-induced inhibition of nonsense mediated RNA decay regulates intracellular cystine transport and intracellular glutathione through regulation of the cystine/glutamate exchanger SLC7A11
por: Martin, Leenus, et al.
Publicado: (2014) -
Rotavirus-induced lncRNA SLC7A11-AS1 promotes ferroptosis by targeting cystine/glutamate antiporter xCT (SLC7A11) to facilitate virus infection
por: Banerjee, Shreya, et al.
Publicado: (2023)