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Mistletoe lectin inhibits growth of Myc‐amplified small‐cell lung cancer

BACKGROUND: Small‐cell lung cancer (SCLC) is the deadliest form of lung cancer but lacks targeted therapies. METHODS: We studied the effect of the natural product mistletoe lectin (ML) in pre‐clinical models of SCLC, focusing on cell lines with amplification of the myc family oncogenes C‐myc and N‐m...

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Detalles Bibliográficos
Autores principales: Shatat, Mohammad A., Gauthier, Betsy, Yoon, Suzy, Yuan, Eric, Yang, Peiying, Narla, Goutham, Dowlati, Afshin, Lee, Richard T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134353/
https://www.ncbi.nlm.nih.gov/pubmed/36562288
http://dx.doi.org/10.1002/cam4.5558