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Intra-arterial verapamil improves functional outcomes of thrombectomy in a preclinical model of extended hyperglycemic stroke

The abrupt hyperglycemic reperfusion following thrombectomy has been shown to harm the efficacy of the intervention in stroke patients with large vessel occlusion. Studies of ours and others have shown thioredoxin-interacting protein (TXNIP) is critically involved in hyperglycemic stroke injury. We...

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Detalles Bibliográficos
Autores principales: Nasoohi, Sanaz, Alehossein, Parsa, Jorjani, Masoumeh, Brown, Candice M., Ishrat, Tauheed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134451/
https://www.ncbi.nlm.nih.gov/pubmed/37124219
http://dx.doi.org/10.3389/fphar.2023.1161999