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Effects of Molecular Crowding on the Structure, Stability, and Interaction with Ligands of G-quadruplexes

[Image: see text] G-quadruplexes (G4s) are widely found in cells and have significant biological functions, which makes them a target for screening antitumor and antiviral drugs. Most of the previous research on G4s has been conducted mainly in diluted solutions. However, cells are filled with organ...

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Detalles Bibliográficos
Autores principales: Gao, Chao, Mohamed, Hany I., Deng, Jieya, Umer, Muhammad, Anwar, Naureen, Chen, Jixin, Wu, Qiao, Wang, Zhangqian, He, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134454/
https://www.ncbi.nlm.nih.gov/pubmed/37125118
http://dx.doi.org/10.1021/acsomega.3c01169